Publications

Elia N, Quinonez M, Wu F, Mokhonova E, DiFranco M, Spencer MJ, Cannon, SC. Potassium-sensitive loss of muscle force in the setting of reduced inward rectifier K+ current: implications for the Andresen Tawil Syndrome. PNAS 2025 122:13, e2418021122.  doi: 10.1073/pnas.2418021122. 

Angelini, M., Savalli, N., Steccanella, F., Maxfield S., Pozzi, S. DiFranco, M., Cannon, S.C., Pantazis, A., Olcese, R., The molecular transition that confers voltage dependence to muscle contraction. Nat Comm, 2025. 16(1): p. 4847.

• Quinonez M, DiFranco M, Wu F, Cannon SC. (2023). Retigabine suppresses loss of force in mouse models of hypokalaemic periodic paralysis. Brain. 146(4):1554-60.
• DiFranco M, Cannon SC. (2022). Voltage-dependent Ca2+ release is impaired in hypokalemic periodic paralysis caused by CaV1.1-R528H but not by NaV1.4-R669H. Am J Physiol Cell Physiol. 323(2):C478-C85.
• Wu F, Quinonez M, Cannon SC. (2021). Gating Pore Currents in Domain III HypoPP Mutations of CaV1.1. J Gen Physiol. 153:e202112946.

• Kubota T, Wu F, Vicart S, et al., Cannon SC. (2020). Hypokalaemic periodic paralysis with a charge-retaining substitution in the voltage sensor. Brain Commun. 2(2): fcaa103.
• Elia N, Nault T, McMillan HJ, et al., Cannon SC. (2020). Myotonic Myopathy With Secondary Joint and Skeletal Anomalies From the c.2386C>G, p.L769V Mutation in SCN4A. Front Neurol. 11:77.
• DiFranco M, Quinonez M, Dziedzic RM, Spokoyny AM, Cannon SC. (2019). A highly-selective chloride microelectrode based on a mercuracarborand anion carrier. Sci Rep. 9(1):18860.
• Heiny JA, Cannon SC, DiFranco M. (2019). A four-electrode method to study dynamics of ion activity and transport in skeletal muscle fibers. J Gen Physiol. 151:1146–1155.
• Elia N, Palmio J, Sampedro Castaneda M, et al., Cannon SC. (2019). Myasthenic congenital myopathy from recessive mutations at a single residue in NaV1.4. Neurology. 92:e1405–e1415.
• Mi W, Wu F, Quinonez M, DiFranco M, Cannon SC. (2019). Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis. J Gen Physiol. 151:555–566.
• Lin MA, Cannon SC, Papazian DM. (2018). Kv4.2 autism and epilepsy mutation enhances inactivation of closed channels but impairs access to inactivated state after opening. PNAS. 115:E3550–E3568.
• Wu F, Quinonez M, DiFranco M, Cannon SC. (2018). Stac3 enhances expression of human CaV1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels. J Gen Physiol. 150:475–489.

• Cannon SC. (2017). An atypical mutation of CaV1.1 supports a common mechanism for susceptibility to hypokalemic periodic paralysis. J Gen Physiol. 149:1061–1064.
• Cannon SC. (2017). Sodium Channelopathies of Skeletal Muscle. In: Handbook of Exp. Pharm., Springer.
• Wu FF, Mi W, Struyk AS, Cannon SC. (2016). Mice with an NaV1.4 sodium channel null allele have latent myasthenia, without susceptibility to periodic paralysis. Brain. 139:1688–1699.
• Nelson BR, Makarewich CA, Anderson DM, et al., Cannon SC. (2016). A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle. Science. 351:271–275.
• Cannon SC. (2015). Channelopathies of Skeletal Muscle Excitability. Compr Physiol. 5:761–790.
• Wu FF, Mi W, Cannon SC. (2013). Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalemic periodic paralysis. Brain. 136:3766–3774.
• Nelson BR, Wu FF, Liu Y, et al., Cannon SC. (2013). The skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility. PNAS. 110:11881–11886.
• Wu FF, Mi W, Hernandez-Ochoa EO, et al., Cannon SC. (2012). A calcium channel knock-in mutant (CaV1.1-R528H) mouse model of hypokalemic periodic paralysis. J Clin Invest. 122:4580–4591.